La inflamación, el estrés oxidativo y el azúcar

Por muy dulce y acaramelado que sea, el azúcar acelera el envejecimiento de tus tejidos y promueve tu resistencia a la insulina, te inflama, te oxida, te «tuesta», pone en peligro la integridad de tus neuronas productoras de dopamina y encima… arenga el crecimiento del cáncer.

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Referencias (por orden de aparición):

Furman, D., Campisi, J., Verdin, E., Carrera-Bastos, P., Targ, S., … & Slavich, G. M. (2019). Chronic inflammation in the etiology of disease across the life span. Nature Medicine, 25(12), 1822-1832.

BIBLIOGRAFÍA RECOMENDADA: Bredesen, D. (2021). The First Survivors of Alzheimer’s: How Patients Recovered Life and Hope in Their Own Words. Disponible en Amazon.

Pizzino, G., Irrera, N., Cucinotta, M., Pallio, G., Mannino, F., … & Bitto, A. (2017). Oxidative Stress: Harms and Benefits for Human Health. Oxidative Medicine and Cellular Longevity, 2017, 8416763.

Taubes, G. (2011). Is Sugar Toxic? The New York Times.

Rada, P., Avena, N. M., & Hoebel, B. G. (2005). Daily bingeing on sugar repeatedly releases dopamine in the accumbens shell. Neuroscience, 134(3), 737-744.

Nguyen, H. P., & Katta, R. (2015). Sugar Sag: Glycation and the Role of Diet in Aging Skin. Skin Therapy, 20(6), 1-5.

Takeuchi, M., Kikuchi, S., Sasaki, N., & Yamagishi, S. (2004). Involvement of advanced glycation end-products (AGEs) in Alzheimer’s disease. Current Alzheimer Research, 1(1), 39-46.

Smith, M. A., Taneda, S., Richey, P. L., Miyata, S., Yan, S. D., Stern, D., Sayre, L. M., Monnier, V. M., & Perry, G. (1994). Advanced Maillard reaction end products are associated with Alzheimer disease pathology. Proceedings of the National Academy of Sciences of the United States of America, 91(12), 5710-5714.

Reddy, V. P., Obrenovich, M. E., Atwood, C. S., Perry, G., & Smith, M. A. (2002). Involvement of Maillard reactions in Alzheimer disease. Neurotoxicity Research, 4(3), 191-209.

Lenoir, M., Serre, F., Cantin, L., & Ahmed, S. H. (2007). Intense sweetness surpasses cocaine reward. PloS one, 2(8), e698.  

Taubes, G. (2018). Contra el azúcar (Ensayo). Disponible en Amazon.

Yudkin, J. (1972 & 2012). Pure, White and Deadly: How Sugar Is Killing Us and What We Can Do to Stop It. Disponible en Amazon.

Lustig, R. (2014). Fat Chance: The Hidden Truth about Sugar, Obesity and Disease. Disponible en Amazon.

Perlmutter, D. (2020). Alzheimer’s: The Science of Prevention. Disponible en

Prinz, R. J., Roberts, W. A., & Hantman, E. (1980). Dietary correlates of hyperactive behavior in children. Journal of Consulting and Clinical Psychology, 48(6), 760-769.

Jones, T. W., … & Tamborlane, W. V. (1995). Mechanisms underlying the adverse effects of sugar ingestion in healthy children. The Journal of Pediatrics, 126(2), 171-177.

Zhang, L., Du Rietz, E., Kuja-Halkola, R., Dobrosavljevic, M., Johnell, K., & Chang, Z. (2022). Attention-deficit/hyperactivity disorder and Alzheimer’s disease and any dementia: A multi-generation cohort study in Sweden. Alzheimer’s & Dementia, 18(6), 1155-1163.

Dobrosavljevic, M., Zhang, L., Garcia-Argibay, M., Rietz, E. D., & Larsson, H. (2022). Attention-deficit/hyperactivity disorder as a risk factor for dementia and MCI. European Psychiatry, 65(1).

Curtin, K., Fleckenstein, A. E., Keeshin, B. R., Yurgelun-Todd, D. A., … & Hanson, G. R. (2018). Increased risk of diseases of the basal ganglia and cerebellum in patients with a history of ADHD. Neuropsychopharmacology, 43(13), 2548-2555.

Fan, H.-C., Chang, Y.-K., Tsai, J.-D., Chiang, K.-L., Shih, J.-H., Yeh, K.-Y., Ma, K.-H., & Li, I.-H. (2020). The Association Between Parkinson’s Disease and Attention-Deficit Hyperactivity Disorder. Cell Transplantation, 29, 963689720947416.

Sadasivan, S., Pond, B. B., Pani, A. K., Qu, C., Jiao, Y., & Smeyne, R. J. (2012). Methylphenidate Exposure Induces Dopamine Neuron Loss and Activation of Microglia in the Basal Ganglia of Mice. PLOS ONE, 7(3), e33693.

Johnson, R. J., Gold, M. S., Johnson, D. R., Ishimoto, T., Lanaspa, M. A., Zahniser, N. R., & Avena, N. M. (2011). Attention-deficit/hyperactivity disorder: Is it time to reappraise the role of sugar consumption? Postgraduate Medicine, 123(5), 39-49.

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